From Gene to Structure to Function
Robinson College, Cambridge, 20-22 September 2000
Final Programme
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From Gene to Structure to Function Robinson College, Cambridge, 20-22 September 2000 Final Programme |
Day 1: Wednesday 20 September 2000
| 0830 - 1000 | Registration | |
| 1000 - 1030 | Coffee
(Balcony) |
|
| 1030 - 1035 | Welcome & Introduction | Dr Rob Russell SmithKline Beecham Pharmaceuticals, Harlow, UK |
| Plenary Lecture | Chair: Dr Rob Russell (SmithKline Beecham, UK) | |
| 1035 - 1130 | Structural Genomics: A New Role of Structural Biology for Functional Genomics | Prof. Sung-Hou Kim
University of California, Berkeley and Lawrence Berkeley National Laboratory, USA |
| Session I:
Target Selection |
Chair: Dr Rob Russell (SmithKline Beecham, UK) | |
| 1130 - 1200 | Completeness in Structural Genomics | Dr John Moult
CARB, Maryland, USA |
| 1200 - 1230 | Protein families of unknown structure in Pfam | Dr Alex Bateman
Sanger Centre, Hinxton, UK |
| 1230 - 1245 | A structural genomics pilot project based on the genome of E.coli | Dr Mirek Cygler Biotechnology Research Institute, Montréal, Quebéc, Canada |
| 1245 - 1300 | A structural genomics pre-pilot project: study of 20 yeast ORFs | Dr Sophie Quevillon-Cheruel CNRS, Orsay, France |
| 1300 - 1415 | Lunch
(Garden Restaurant) |
|
| Session II:
Expression, Purification, Crystallisation |
Chair: Prof. Joël Janin (CNRS, Gif-sur-Yvette, France) | |
| 1415 - 1445 | The Berlin-Based "Protein Structure Factory" Project | Dr Udo Heinemann
Protein Structure Factory, Berlin, Germany |
| 1445 - 1515 | High Throughput Expression for Structural Analysis:- Pitfalls & Prospects | Dr Owen Jenkins SmithKline Beecham Pharmaceuticals, Harlow, UK |
| 1515 - 1530 | Crystallization for structural genomics: what we have and what is missing | Dr Naomi Chayen Imperial College, London, UK |
| 1530 - 1545 | Structural Genomics at Structural GenomiX | Dr Tom Peat Structural GenomiX, San Diego, USA |
| 1545 - 1615 | Tea
(Balcony) |
|
| Session III:
Structure Determination I |
Chair: Prof. Guy Dodson (University of York / NIMR, Mill Hill, UK) | |
| 1615 - 1645 | Protein Modules - Targets for Structural Genomics and Beyond | Prof. Iain Campbell
University of Oxford, UK |
| 1645 - 1715 | From Xray maps to protein function | Dr Tom Oldfield
Molecular Simulations Inc., University of York, UK |
| 1715 - 1745 | High Throughput X-ray Crystallography for Drug Discovery | Dr Harren Jhoti Astex Technology, UK |
| 1800 - 1900 | Drinks reception, sponsored by Molecular Simulations Inc. | |
| 1900 - 2100 | Dinner
(Dining Hall) |
Day 2: Thursday 21 September 2000
| Session IV:
Structure Determination II |
Chair: Dr Gabriele Varani (MRC, Cambridge, UK) | |
| 0900 - 0930 | Underlying methodology for high-throughput structure determination | Dr Victor Lamzin
EMBL, Hamburg, Germany |
| 0930 - 1000 | Structures, Function, Weak Interactions, and NMR | Dr Hartmut Oschkinat
FMP, Berlin, Germany |
| 1000 - 1030 | Structure-based Functional Genomics | Dr Gaetano Montelione
Rutgers University, New Jersey, USA |
| 1030 - 1100 | Coffee
(Balcony) |
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| Session V:
Structure Determination & Deposition |
Chair: Prof. Janet Thornton (University College London) | |
| 1100 - 1130 | RIKEN Structural Genomics Projects | Prof. Shigeyuki Yokoyama
RIKEN, Yokohama, Japan |
| 1130 - 1200 | Structural Proteomics in Prokaryote Systems | Dr Aled Edwards
University of Toronto, Canada |
| 1200 - 1230 | The European Macromolecular Structure Database (EMSD) and Structural Genomics | Dr Geoff Barton
European Bioinformatics Institute, UK |
| 1230 - 1245 | Structural Genomics: Building a Structural Foundation for Biology | Dr Jean-Denis Pédelacq Los Alamos National Laboratory, USA |
| 1230 - 1245 | No fold recognition method is always best! Results from studies of different fold recognition methods | Dr Arne Elofsson Stockholm Bioinformatics Centre, Sweden |
| 1300 - 1415 | Lunch
(Garden Restaurant) |
|
| Session VI:
Functional Genomics |
Chair: Dr Robert Cooke (GlaxoWellcome, Stevenage UK) | |
| 1415 - 1445 | Structural genomics in the context of other genome research | Dr Richard Durbin
Sanger Centre, UK |
| 1445 - 1515 | Analysis of gene expression; bridging the gap from sequence to function | Dr Tom Freeman
Sanger Centre, UK |
| 1515 - 1545 | Functional Genomics Using 3-D Structures: From ORFANs to Unknowns | Dr Jean-Michel Claverie
Structural & Genetic Information Lab., Marseilles, France |
| 1545 - 1600 | (beta/alpha)8 barrel enzymes and the evolution of function & pathways | Dr Richard Copley EMBL, Heidelberg, Germany |
| 1600 - 1615 | Practical limits of function prediction | Mr Damien Devos CNB-CSIC, Madrid, Spain |
| 1630 - 1830 | Posters and Commercial Exhibitions Tea (16.15 - 16.45) Wine served on Balcony (15.30 - 18.30) sponsored by Sun Microsystems |
|
| 1900 | Conference Dinner, sponsored by Inpharmatica
(Main Dining Room) |
Day 3: Friday
22 September 2000
| Session VII:
Structural Bioinformatics I |
Chair: Dr Alfonso Valencia (CNB-CSIC, Madrid, Spain) | |
| 0900 - 0930 | Further Developments Towards Reliable Genome-scale Fold Recognition | Prof. David Jones
Brunel University, London, UK |
| 0930 - 1000 | Exploiting Protein Structure in Genome Annotation | Dr Mike Sternberg
Imperial Cancer Research Fund, London, UK |
| 1000 - 1030 | The Evolution and Structural Anatomy of the Small Molecule Metabolic Pathways in Escherichia coli | Dr Sarah Teichmann
University College, London, UK |
| 1030 - 1100 | Coffee
(Balcony) |
|
| Session VIII:
Structural Bioinformatics II |
Chair: Prof. Rod Hubbard (University of York, UK) | |
| 1100 - 1130 | What can structure tell us about bioinformatics? | Dr Peter Artymiuk
University of Sheffield, UK |
| 1130 - 1200 | Evolution of function in protein superfamilies, from a structural perspective: implications for genome annotation | Dr Annabel Todd
University College, London, UK |
| 1200 - 1230 | New developments concerning the Swiss-PdbViewer sequence to structure workbench | Dr Nicholas Guex
Glaxo Wellcome, Geneva, Switzerland |