Welcome to the website for the 18th International MGMS Meeting: Modelling Biomolecular Mechanism: From States to Processes at the Atomic Level to be held on 5th - 8th April 2000 at the University of York,UK
A central goal of biomolecular science is understanding the molecular processes that underpin biological function. The methods of Structural Biology can determine structures representing important discrete states in a process such as reactant, product and intermediate. These (predominantly) static approaches are complemented by spectroscopic (and other experimental) techniques which address the dynamics of a process.
Modelling plays a powerful role in the interpretation and interpolation of experiment and provides insight into mechanism and function. In recent years important methodological advances have been made in biomolecular modelling and simulation which address processes directly. These new techniques open up new classes of problems inaccessible to traditional equilibrium simulation methods, significantly extending the spatial and temporal scope of applications.
This meeting focuses on computational approaches to investigating conformational and reactive processes in biomolecules, covering theory, methods and applications. A key aspect of the meeting is to explore the interface with experimental approaches, highlighting the application and prospects of single molecule and time-resolved techniques.
The meeting will provide an important and timely opportunity to review and stimulate discussion across the many disciplines addressing the mechanistic aspects of structure-function relationships in biological processes at the atomic level.
| 5th April | Meeting Starts (11am Registration Open; 2pm Programme Start) |
| 7th April | MGMS AGM (5:00pm); Conference Dinner at National Railway Museum, York (7.30pm) |
| 8th April | Meeting Ends (4pm) |