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Registration will open at 9am, and refreshments will be available.

Session 1, Chair: Steve Maginn, CCG
10.00-10.10	Steve Maginn	CCG	Opening remarks
10.10-10.40	Miles Congreve	Heptares	Structure and fragment based drug design for GPCRs using StaRs
10.40-11.10	Dave Sheppard	BioFocus	Shape-based profiling of compound libraries
11.10-12.00	Tom Blundell	University of Cambridge	Plenary Lecture: The structural interactome and drug discovery
12.00-12.20	MGMS AGM - All welcome
12.20-13.20	Lunch and exhibition
Session 2, Chair: Shozeb Haider, Queen's University, Belfast
13.20-14.10	Gerhard Klebe	University of Marburg	Plenary Lecture: Title TBC
14.10-14.40	Ian Williams	University of Bath	Kinetic isotope effects, transition states and drug design
14.40-15.10	Refreshments
Session 3, Chair: Chris Richardson, BioFocus
15.10-15.40	Gergely Toth	University of Cambridge	Targeting monomeric form of intrinsically disordered proteins by small molecules as a potential therapeutic approach for neurodegenerative diseases
15.40-16.10	Darren Green	GSK	How to combat lipophilicity in lead discovery & optimisation
16.10-16.40	Prof Jonathan Essex	University of Southampton	Water and fragment binding by free energy calculations
16.40-16.50	Chris Richardson	BioFocus	Closing Remarks